Grape Science Center

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About Us

About Us

Grape Science Center

Brought to you by Welch Foods, Inc. (“Welch’s”) and National Grape Cooperative Association, Inc., the Grape Science Center is a valuable resource for health professionals and others to learn about the growing research behind the Concord grape’s role in health. This website is designed to present and help translate the latest science behind these delicious and nutritious grapes. We hope you will enjoy discovering more about the power of the Concord grape to fuel healthy lifestyles.

Welch's and National Grape Cooperative

Headquartered in Concord, Massachusetts, Welch’s is the processing and marketing subsidiary of the National Grape Cooperative. Welch’s is owned by 1,150 family-farmers across America and in Ontario, Canada, who make up this cooperative, and who are responsible for growing the Concord and Niagara grapes that are pressed to produce Welch’s juices and other grape-based products. At the heart of Welch’s are the delicious and inherently healthy Concord grape, and the family-farmer owners who grow it.

Have a question for us, want to make a comment or offer a suggestion? Please contact us by email at askwelchs@welchs.com.

Grape Research Overview

For nearly 20 years, researchers have been exploring an important mix of plant nutrients – polyphenols – found in Concord grapes and the effects they have on the body, including possible benefits in supporting cardiovascular health. In addition, emerging research is being conducted to determine whether Concord grapes play a role in supporting a healthy mind and immune system. See the research.

 


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An observational study, usually a retrospective study (a study that looks backward in time) that compares two groups of people: 1) those with the specific condition (e.g., disease) being studied (cases) and, 2) a similar group of people without that condition (controls). Researchers compare these two groups of people and important characteristics, such as certain lifestyle choices, to determine what factors may be associated with the condition under investigation.

A type of study that often includes patients with specific health conditions who could benefit from receiving a new treatment. These studies can also be performed in healthy subjects. The end goal of a clinical study (also called clinical research or clinical trial) is to determine effectiveness and safety of a health intervention in humans.

An observational study, usually prospective (looking forward), that follows a group of similar people over time. The goal is to determine which factors and exposures affect the development of a specific outcome or health condition (e.g., disease) during the study’s time period.

A type of observational study, often given as a survey, that examines a group of subjects during a single occasion, or over a very short period of time. This type of study aims to describe the relationship between health-related conditions (e.g., metabolic syndrome, hypertension) and other factors that exist in the general population (e.g., dietary intake, physical activity levels), during a particular time period.

A type of study in which researchers simply observe subjects and measure the associations between certain characteristics (e.g., fruit/vegetable intake) and specific outcomes (e.g., obesity). Examples of observational studies include case-control studies, cross-sectional studies, and cohort studies. While these studies gather important information, they cannot prove that a specific treatment or factor affects health.

A small scale, preliminary study that is conducted to determine the potential for a larger study.

A stage of research that often occurs prior to trials involving humans. This type of research can help determine mechanisms of action of a treatment, or how the treatment is causing the effect, as well as help ensure the safety of treatment in subsequent human trials.

In vitro
Testing performed in a controlled environment, such as a test tube or a Petri dish, instead of living organisms. In vitro literally means "within the glass" in Latin.

Ex vivo
These experiments are performed on tissue (e.g., animal or human cells) taking place outside of the organism, such as in a laboratory setting. In Latin, this means "out of the living."

In vivo
These tests are done on whole, living organisms. Technically, animal and human testing are two forms of in vivo research, which means "within the living." These experiments may be performed outside of a laboratory setting.

A study designed to provide the most credible information about the cause and effects of treatment. These types of studies are recognized as unbiased because they involve the random assignment of treatments to subjects being studied.

Bias
The tendency throughout any stage of research to generate findings that may not reflect "true values." In clinical trials, researchers try to avoid many kinds of bias, including selection by randomizing subjects, measurement by creating placebos and performing blind trials, and confounding by carefully designing the study and analyzing the findings.

Blind
Study in which subjects do not know whether they receive the treatment or the placebo, which assists in prevention of bias. Double-blinded studies are a higher level of scientific rigor because neither the participants nor the investigators know who is receiving the treatment or the placebo. A double-blind crossover study means each participant undergoes both the treatment and control scenario, typically with a wash-out period in between.

Placebo-controlled
Study that allows researchers to isolate the effect size of the treatment by comparing a group given a simulated treatment (e.g., grape flavored drink) to those with the real treatment (e.g., Concord grape juice), which reduces measurement bias. The placebo should match as closely as possible to the treatment without containing the active ingredients.

Randomized
Study involving participants who are randomly assigned to either the treatment or the placebo group, reducing selection bias.